Raj: They're going to digitally add a supernova they say its the perfect metaphor for my incandescent talent.
Sheldon: Yes, a giant ball of gas that collapses on itself.

Raj: (Talking about Leslie Winkle) I think she's smoking hot.
Howard: I'd hit that!
Sheldon: You'd hit particulate soil in a colloidal suspension. (Seeing Howard's confusion) Mud.

Leonard: Okay, don't take this as a criticism but you do have that over exposed to gamma radiation thing going on.
Penny: What?
Leonard: Usually your the easy going Bruce Banner but when you get angry you turn into (makes growling noise).
Penny: I turn into a bear?
Leonard: Gamma radiation, Bruce Banner; you didn't get the Incredible Hulk from that?

Penny: Whats Sheldon's deal? Is it girls, guys, sock puppets?
Howard: We operate on the assumption that Sheldon has no deal. Though we have many theories about how he might reproduce. I'm an advocate of mitosis.
Penny: What?
Howard: I believe that one day Sheldon will eat an enormous amount of Thai food and spilt into two Sheldons.

Wolowitz: Have you thought about putting him in a crate when you're out of the apartment?

Penny: Get them down!
Sheldon: Apologize.
Penny: Never.
Sheldon: Then you just get a very long stick and play panty pinata!

Penny: Leonard, look. Sheldon's hugging me!
Leonard: It's a Saturnalia miracle.

Sheldon: I'm baaaaaaaaaaaaaaaack.

Penny: It's just this is only our first date.
Leonard: Well, why don't we just figure out where we're going, and when we want to get there, and then rate of speed equals distance over time, solve for 'r'.
Penny: Or we could just wing it.

Howard: You know the old saying: pasty and frail never fail.

Leonard: Well, it looks like you're caught between a rock and a crazy place.
Sheldon: I hate when that happens.

Raj: I know, I am resplendent like the noonday sun, am I not?

Leonard: Sheldon, would you be prepared on a non-presidential basis, to create an emergency ad-hoc slurpee/icee equivalency?
Sheldon: Oh Leonard, you know I can't do that.

Penny: Okay, I got a box, but there's no key in here. Just letters.
Sheldon: That's the wrong box. Put it back.
Penny: Oh, Sheldon, are these letters from your grandmother?
Sheldon: Don't read those letters.
Penny: Oh, look, she calls you Moon Pie. That is so cute.
Sheldon: (shrieking) Put down the letters!

Sheldon: Leonard, let me tell you something. Personal robots cannot get here soon enough.