Bernadette: (Sounding like Mrs. Wolowitz) He wants butter!

Leonard: It turns out she really knows how to help a guy loosen up and have a good time. Although, truth be told, my groin is a little worse for wear.
*Sheldon karate chops Leonard*
Leonard: Why did you do that?
Sheldon: To send a message: She is not for you!
Leonard: What?
Sheldon: Not for you!

Wolowitz: You have to wonder about grown men who play with toy trains.

Sheldon: All these years I've been so wrong. The tinier the trains, the more concentrated the fun.

Mrs. Wolowitz Hey, if she's willing to give the milk away for free, who am I to say no?

Leonard: Aren't you going with Sheldon?
Amy: No, I have no interest in model trains, stores that sell them, nor their heartbreaking clientele.

Leonard: Well, I have some work to do, so-
Amy: I can't imagine that would disturb me. Carry on.
Leonard: Okay. Wouldn't you be more comfortable at home?
Amy: Not really, no.
Leonard: All righty then. Guess I'll just get started.
Amy: Leonard, please. I don't need the running commentary.

Amy: Should I go? I have been told sometimes I overstay my welcome.
Leonard: What? Who told you that?
Amy: Well, most recently my gynaecologist.

Bernadette: That's pretty big talk for a man with a closet full of magic tricks at his mother's house.

Amy: I need someone to accompany me to the wedding of Dr. Moranelli and Dr. Gustafson this Friday. They're kind of the Brad and Angelina of the primatology department.
Leonard: Wouldn't you rather bring Sheldon?
Amy: I would, but the last wedding we went to was a disaster. He behaved like a child the entire time.
Sheldon: Not my fault. You said there'd be other scientists there my age.

Mrs. Wolowitz: Frankly, after all your sleepovers with the little brown boy, a girl is a big relief!

Penny: You're a brain scientist. Can you explain to me why a brilliant man likes playing with toy trains?
Amy: Not without cutting his head open, no.

Leonard: I just can't figure out what happened. I put my left leg in, I took my left leg out, I put my left leg in, and something just snapped.
Amy: The hokey pokey is a young man's game.

Leonard: Who wants the last dumpling?
Penny: Ooh, me.
Sheldon: Penny, a moment. We just had Thai food. In that culture, the last morsel is called the krengjai piece, and it is reserved for the most important and valued member of the group.
Penny: Thank you all for this high honor.

Howard: All right, honey, if were gonna make the movie, we should go. (Raj stands up) This may be hard for you to hear, but when I say honey, I mean my fiance. (Raj whispers to Howard) Yeah, well, now it means her.
Bernadette: It's okay if he wants to come.
Howard: Fine. But next time, we get a sitter.