Bernadette: Hey, Howie, how you feeling?
Wolowitz: Better. Much better. The other astronauts held me down, gave me a shot. Oooh. Attention, people of Earth. Tonight, there will be two moons in the sky.
Bernadette: Howie, stop that. NASA's watching this! Put your pants back on!

Sheldon: If you're going to replace Wolowitz, I need to know a little bit more about you.
Stuart: All right.
Sheldon: Wolowitz went to MIT. What's your educational background?
Stuart: I went to art school.
Sheldon: Equally ridiculous. Let's go.

Sheldon: Penny, please don't hurt my friend.

Sheldon: Settle down there, fake Wolowitz. No one likes a kiss-up.

Amy: If Sheldon proposed to me during sex, my ovaries would grab onto him and never let go.

Leonard: I know what the anthropic principle is.
Sheldon: Of course. I just explained it to you. Now, where do you stand on it?
Leonard: Where do you stand on it?
Sheldon: Strongly pro.
Leonard: Then I believe that God created the world in six days and on the seventh he made you to annoy me.