Howard: Hang on, I know a place where you could you stay and earn some money at the same time.
Stuart: Great!
Howard: I just have to warn you: it will involve humiliation, degradation and verbal abuse.
Stuart: So, what's the catch?

Sheldon: You tracked my phone?
Leonard: Yeah.
Sheldon: Boy, you chase one balloon for three miles.
Penny: We were worried about you.
Sheldon: Don't be melodramatic. I'm just getting on a train and leaving for ever.

Leonard: So, listen. There was something I was hoping to float past you. Now that Penny and I are engaged, I thought we might want to talk about our living arrangements.
Sheldon: Of course. She's spent many nights here, and you're worried about preserving the myth of her virginity before the wedding.
Leonard: I'm not.
Sheldon: Good. Because not only has that ship sailed, if it hit an iceberg countless men would perish.

Penny: He can take care of himself. We went over Stranger Danger and gave him that whistle.

Sheldon: Have you had intercourse?
Raj: No.
Sheldon: Well stick to your guns. There'll be a lot of pressure.

Sheldon: Thanks for coming with me.
Raj: Thanks for inviting me when everyone else said no.

Raj: But before I take my shirt off, I need like ten minutes to do some crunches.

Raj: Aren't you going to get 3D glasses?
Sheldon: I brought my own. No sense in risking "bridge of nose Herpes".
Raj: Is that a real thing?
Sheldon: Well, until they invent nose condoms, I'm not finding out.

Leonard: Come on. How can you be sad when you're going home with all five foot six of this?
Penny: You think you're five foot six? That's funny.

Raj: Wouldn't you be upset if you saw Amy out with someone else?
Sheldon: Can't happen. We have an iron-clad relationship agreement which precludes her from sexual contact with anyone other than me.
Raj: But you don't have sex with her either.
Sheldon: Slick, huh?

Raj: If she isn't going to use it, why are we doing this?
Howard: She'll use it. All I need is to rig it with a fishing pole and a honey-baked ham.

Leonard: So I'm like a bran muffin?
Penny: What? No, that's not what I'm saying.
Leonard: No, that's exactly what you're saying. I'm the boring thing you're choosing because I'm good for you.
Penny: What does it matter? I'm choosing you.
Leonard: It matters a lot. I don't want to be a bran muffin. I want to be a cinnabon, a strawberry pop tart. Something you're excited about, even if it could give you diabetes.
Penny: Sweetie, you can be any pastry you want.

Sheldon: I thought that subject had run its course, so I changed it. It's called reading the room, Amy.

Howard: Would you like me to play some Polish music while you carry her to the toilet?
Bernadette: You are a putz.
Howard: As advertised.

Sheldon: How many women have you had dates with?
Raj: Eleven.
Sheldon: How many of those women did you think would become your perfect companion?
Raj: Eleven.
Raj: Wait, do I count the 200lb Sailor Moon girl that Howard and I had a threesome with at Comic-Con?
Sheldon: Sure.
Raj: I'll stick with eleven. She liked Howard better.