Leonard: You didn't lose anyone when you met Amy.
Sheldon: The study refers to romantic partners. That's not the way I would categorize the two of us.

Raj: You guys kiss and hold hands.
Leonard: I've seen him do it. It's not romantic.

Raj: I'm not the kind of guy who drops his friends because he's in a relationship.
Leonard: What happens if she doesn't like us?
Raj: Hey, you're my dear friends. You'll get a Christmas card for a couple of years and then you're dead to me.

Leonard: Wow, Raj, you were not lying about her.
Raj: I told you she exists!

Sheldon: It's like when I thought there was possum in my closet. Did I sit around wondering? No, I sent Leonard in with a pointy stick and a bag.
Leonard: I killed his chewbacca slippers.

Amy: It would make me so happy if you said things like that.
Sheldon: We got an 8.2. Trust me, you're happy.

Raj: I love how they put a waterfall at centerfield. It really ties the whole stadium together.
Penny: Look at you talking sports.

Raj: You suck, Wolowitz!
Sheldon: He makes a valid point!

Amy: It's a good thing I'm not wearing flag underwear right now, cause there's about to be a fire.

Bernadette: It's not that hard. You just look to where you want to throw it, step towards where you want to throw, and throw it.
Howard: That's your help? That's like saying "Here's how you fly a plane: get in the airplane and know where you want to go, and fly it."

Amy: So when you guys plan on getting married?
Penny: We're not sure, but I wanna wait long enough to prove to my mother I'm not pregnant.

Penny: Well, a relationship is more complicated than a french fry.
Sheldon: Not according to the work of Berscheid, Snyder & Omoto.
Penny: Oh, what did those rascals do now?

Penny: Well, that's not good. You being blindly infatuated with me was the rock we were building this relationship on.

Amy: Here they go fighting again. You'd never hear her talk that way to sauvignon blanc.

Raj: So you never played baseball as a kid? Not even little league?
Howard: Well, I was going to but the day of tryouts I found my dad's Playboy collection. Threw my arm out.