Meemaw: Let her go. And under no circumstance will you give her that engagement ring.
Amy: What ring?
Leonard: Maybe we should give them some privacy.
Penny: Yeah, yeah, yeah. You go ahead. I'll catch up with you.

Meemaw: Sheldon, tell this girl that my ring will never be on her finger.
Sheldon: Yeah, I'm gonna opt out of that one, too.

Sheldon: Look, let's all let's remain calm and analyze this situation. Now, I realize that you've only known each other for less than a day, but is it possible this crankiness is because your cycles have synced?
Meemaw: You leave the room and let the grown-ups talk. Now!
Amy: Don't speak to him like he's a child.
Sheldon: Thank you. Now, I'm gonna go next door and play with Leonard.

Amy: Look, I get that you're protective of your grandson, but he's an adult now. Maybe I understand what he needs better than you do.
Meemaw: I appreciate your honesty, dear.
Amy: Thank you.
Meemaw: And here's some more honesty: I don't like you very much.
Amy: Well, maybe I don't like you either.

Meemaw: So, Penny, I understand you have a new job.
Penny: Yes, I'm a pharmaceutical sales rep.
Meemaw: Oh. It's so wonderful that you modern gals can have it all. A husband and a full-time career.
Amy: I have a relationship and a full-time career, too.
Meemaw: That doesn't bode well.
Amy: Why not? You just said it's okay for her to work.
Meemaw: Well, Leonard doesn't need as much tending to as Sheldon does. And as Moonpie explained, Leonard's work is more of a hobby.
Leonard: That's my best friend.

Meemaw: Thank you, Moon Pie.
Amy: Uh, I'm curious. Why do you call Sheldon "Moon Pie?"
Meemaw: 'Cause he's so nummy-nummy.
Leonard and Penny: She could just eat him up.

Penny: Constance, are you sure I can't pour you some wine?
Meemaw: Oh, no wine for me. Sheldon's bringing me my whiskey.
Sheldon: Here you go, Meemaw. I made it just how you like - a lot in a glass.

Sheldon: No, no, no, no, no, no, no, no. You have to like each other. Well, we have a 4:30 reservation at Applebee's.
Amy: I think I should leave.
Sheldon: But why? Other than you two fighting, we're having such a good time.

Claire: Do you think I could pick your brain for my movie some time? It's animated sci-fi for kids.
Raj: Sure. I love animated movies.
Howard: He does, and he has the Lilo & Stitch collector plates to prove it.
Raj: Excuse me for wanting a little magic in my life.

Raj: Yeah, I get that. I'm a scientist / party planner / small-dog enthusiast / guy who probably should have stopped at scientist.

Raj: Well, I've seen you here before, Claire.
Claire: It's my first time. I'm looking for inspiration for this movie I'm writing.
Howard: You're a screenwriter?
Claire: Well, screenwriter / bartender / a month away from living in my car.

Howard: What are you doing? You have a girlfriend.
Raj: So?
Howard: So, how do you think she'd feel about you helping a beautiful girl with her screenplay?
Raj: I wouldn't say she's beautiful.
Howard: Really? You don't think she's attractive?
Raj: I do. I just wouldn't tell my girlfriend.

Amy: Well, this is so nice. He's so excited to have you here and-
Meemaw: Okay, now let's you and me get something straight. He may think that I came to bake him cookies, but the real reason is to size you up.
Amy: S-S-si-Size me up?
Meemaw: Sheldon's mother may be okay with you, but I'm not so easy.
Amy: Well, I-I'm I'm sure you'll like me once you get to know me.
Meemaw: Oh, you better hope so.

Sheldon: A Texas Special cattle and calf car train set with authentic horn and bell! Thank you, Meemaw!
Meemaw: Oh, you're welcome, Moonpie.
Sheldon: Amy, why don't you look excited? You get to watch me play with this!

Sheldon: Oh, well, you two sit down and get to know each other. I'll get your room ready.
Meemaw: Oh, now don't you go looking through my suitcase for presents.
Sheldon: If I did, would I find any?
Meemaw: Maybe. But you also might find my brassieres and bloomers.
Sheldon: That's a risk I'm willing to take!