Sheldon: I may have lost my guidance system and my girlfriend, but I still have a colon full of yesterday's meals to keep me company. Although, thanks to your high-fiber breakfast, I'm sure that'll be leaving me, too.

Amy: Comfy?
Sheldon: Oh, I'm just happy I don't know what this memory foam remembers.

Sheldon: I am not proud of this. But I have been envious of your recent success.
Bert: Wow, I won the MacArthur Grant, everyone's jealous of me. Once I get LASIK, I'll be out of things to wish for.

Amy: I made your favorite oatmeal - plain.

Bernadette: It's okay, I'm just being emotional about this. Can you not tell Howard?
Stuart: Well, don't you think it'd be healthier if you told him what's going on with you?
Bernadette: Don't you think it'd be healthier if you had your own apartment, grown man?
Stuart: Your secret is safe with me.

Bernadette: You know, I just read that a team at MIT developed a device that helps people read human emotions.
Leonard: And you think we can get those guys to reprogram Sheldon? Cool.

Lucy: Can I just say something? Going out with Raj was one of the best things that ever happened to me.
Raj: Yes, I'll take you back.
Lucy: It's like I needed to go through that experience to know what exactly I don't want in a man.
Raj: That's hard to hear, but I'll still take you back.

Penny: Well, it's like that science thing. For every action, you have a gigantic and annoying reaction.
Leonard: Just when I thought you couldn't get any hotter.

Penny: Does the baby have a name yet?
Howard: We have named her Halley.
Penny: Oh!
Leonard: Oh, like Halley's comet.
Howard: Exactly. Also like the comet, Bernadette said she's not gonna have sex with me for another 75 years.

Penny: Uh, what's new?
Zack: Oh, tons of stuff. Put artificial grass in my backyard, got engaged, had a scary mole that turned out to be Sharpie.
Penny: Well, congratulations.
Zack: That's what my dermatologist said.
Penny: No, on getting engaged, good for you.
Zack: Oh, thanks.

Penny: She said not to come. It's gonna be a while.
Amy: (sighs) Well, first deliveries can be slow.
Sheldon: I am starting to rethink the Flash onesie I bought this kid.

Raj: It looks like a map from Dungeons & Dragons.
Howard: Mm. Except the creature in the crib is a level-nine poop monster.

Bernadette: Not every girl dreams about being a mom. Sometimes you think you're never gonna have kids and one day you wake up and you're pregnant. And it doesn't matter that your career's going great right now and that you and your husband never even got to go anywhere taped to a dog!

Leonard: You know what? There is one thing I would like.
Sheldon: Yeah, take whatever you want.
Leonard: I would like to keep the official flag of our apartment.
Sheldon: But you don't even like flags.
Leonard: Yeah, I like this one.
Sheldon: But I designed it.
Leonard: But you made me order it because you were "too well-known" in the flag community and they'd jack up the price.
Sheldon: But you don't even understand its symbolism.
Leonard: Oh, I do. The-the field of blue represents you being miserable, and the lion sticking its tongue out means I'm happy about it.

Sheldon: Well, this is highly insulting.
Amy: Sheldon, don't overreact.
Sheldon: I'm the child she was worried about? I have a brother and sister whose combined intellectual wattage couldn't power a potato clock ... if I spotted them the potato.