Amy: Well, if you're nervous about the sleeping arrangements, maybe we should talk about it.
Sheldon: Okay. Talk.
Amy: Well, I imagine one of your concerns might be coital expectations.
Sheldon: Wow, no foreplay or anything, just right to it.
Amy: Look, I know this experiment is a big step outside of your comfort zone. So why don't we take being physical off the table and maybe later on, once we're more settled in, we can revisit it.
Sheldon: You're really okay with that?
Amy: I've never lived with someone, either. This is a lot for me, too.

Sheldon: Enjoy having the place to yourselves.
Leonard: You enjoy your mission to boldly go where no man has gone before.
Sheldon: It's Penny's bedroom. Plenty of men have gone before.

Sheldon: Oh, don't forget. Tuesday the air filters need to be changed.
Penny: Yeah, you wrote it on my hand.

Sheldon: Oh, and every other day, check the water level on the avocado pit.
Leonard: I'm on it. Fifteen years from now, we'll make guacamole together.

Howard: So you know the sex of our baby, and we don't?!
Raj: Flip a coin. You got a fifty-fifty shot.

Raj: This is not a problem, okay? If you don't want to know, I don't have to tell you.
Bernadette: We don't want you to know!
Raj: Okay, well, that's a problem.

Penny: You know, I'm very proud of you for trying to live with Amy.
Sheldon: Oh, thank you. Of course, the ideal way to conduct this experiment would be with four pairs of identical Sheldons and Amys. One pair that was neither dating nor living together. One pair that was dating but not living together. One pair that was living together but not dating. And then, of course, one pair that was living together and dating. Although, with that many Sheldons, it'd be such a party, we'd never get anything done.
Penny: That was a cute story.

Penny: So, uh, what did you want to ask me?
Sheldon: Well, you've lived with your significant other for some time. I would like this experiment to go well. Are there any insights you can share?
Penny: Mm. Well, the biggie is, if she has an insane roommate, kick him out as soon as possible.
Sheldon: You know, Leonard and I were very happy before you came along.

Amy: You've been roommates with Sheldon forever. Do you have any advice?
Leonard: I'm trying to think of an answer that won't stop you from doing this.

Sheldon: I accept this five-week mission to share a living space with my girlfriend.
Amy: Oh, this is so exciting.
Sheldon: Well, now, don't be surprised if, like Star Trek, it's canceled in three.

Raj: I have to say, I am happy with your ob-gyn.
Howard: Cool. 'Cause she says you're doing a great job as "weird friend who doesn't have to be at every appointment."

Raj: I'm the son of a gynecologist. I could be helpful.
Bernadette: It would help if you stopped telling me I have a textbook cervix.
Raj: The polite response is, "Thank you for noticing."

Bernadette: Let me see the sonogram again. (laughs) Oh, yeah, that's a good-looking baby for a little gray blob.
Howard: Yeah, we could name him Blobert.
Bernadette: What if it's a girl?
Howard: Bloberta. Or Blobbi with an "I."

Bernadette: Are we being silly not finding out the sex?
Howard: Yeah, I was just thinking the same thing.
Raj: If you want, you can find out right now.
Bernadette: Hmm. The doctor's gone for the day, so it doesn't matter.
Raj: Or somebody else knows because they saw it in the folder.
Bernadette: You looked in our folder?!
Raj: It was an accident. The doctor left the folder out on her desk. It's not my fault I opened it and looked.

Sheldon: What if living together kills the romance?
Penny: Okay, you guys had sex one whole time. Nothing can put out a fire like that.