Penny: You may be right about me and Leonard.
Sheldon: Of course I'm right What are the odds I'd be wrong twice in one week?
Penny: No, I mean, we can always go back to being friends.
Sheldon: I just said that. This conversation has started to circle. Meeting adjourned.

Leonard: Hey. What's going on?
Sheldon: Oh, you'd like to catch up on the events of the day. All right. Well, there was a half-hour wait at the bank to get into my safe deposit box, I was forced to talk to Penny about your sexual problems, and, oh, yes, in a moment filled with biblical resonance, pride wenteth before my fall, causing my Flash 123 to goeth to Wolowitz.

Penny: Sheldon, you know, I do understand what you're going through.
Sheldon: Really? Did you just have the Nobel Prize in Waitressing stolen from you?

Howard: Sheldon, you remember the first few weeks we were looking for magnetic monopoles and not finding anything, and you were acting like an obnoxious, giant dictator?
Raj: I thought we were going to be gentle with him.
Howard: That's why I added the '-tator'.

Sheldon: Hello, Penny. I realize you are currently in the mercy of your primitive biological urges. But, as you have an entire lifetime of poor decisions ahead of you, may I interrupt this one?

Sheldon: But evolution is not opinion, it's a fact.
Mary Cooper: And that is your opinion.
Sheldon: [to Leonard, Howard and Raj] I forgive you, let's go home.

Raj: I like the new look.
Howard: Thanks. I call it the Clooney.
Raj: I call it the Mario and Luigi but whatever.

Leonard: Would you please take that stupid hat off?
Howard: No, I want to blend in.
Raj: To what? Toy Story?

Sheldon: I don't know which arctic expedition you guys were on, but I thought it was a hoot and a half.

Howard: Damn it! I should've gone over and told her we were back.
Raj: Yeah, it was first come first serve.

Sheldon: No mother, I could not feel your church group praying for my safety. The fact that I am home safe does not prove it worked. That logic is post hoc ergo propter hoc. No, I'm not sassing you in Eskimo talk.

Wolowitz: I would like a slippery nipple.

Howard: (Southern Accent) If y'all don't mind, I got a hankering for a lone star beer.
Mary: There's no alcohol in this household, stop talking like that, and lose the hat.
Howard: Sorry, I'll take a diet yoo-hoo if you have one.
Mary: You'll take a Coke.

Howard: I can't believe we spent three months in that frozen hell.
Raj: It's like a snowy nightmare from which there's no awakening.

Sheldon: If this is about the night the heat went out, there's nothing to be embarassed about.
Raj: It's not about that.
Howard: We agreed to never speak of it again.
Sheldon: So we slept together naked. It was only to keep our core body temperatures from plummeting.
Howard: He's speaking about it.
Raj: For me it was a bonding moment.