Leonard: You want to hear something weird?
Penny: Sure.
Sheldon: In the year 2000, Pope John Paul II was named an honorary Harlem Globetrotter.
Leonard: What are you talking about?
Sheldon: You asked Penny if she wanted to hear something weird.
Leonard: Yeah, because I have something weird to tell her.
Sheldon: Oh. I thought it was a game.

Leonard: Hey, how about if we pretend we're actually on a first date? See how that goes.
Penny: Okay.
Leonard: So, Polly, tell me about yourself.
Penny: It's Penny.
Leonard: Oh, sorry, yeah. Awkward.

Amy: Seven o'clock, right on time.
Sheldon: It's not an accident. I waited outside your door for twenty minutes.

Raj: Would you look at this? I paid twenty five dollars to some kid on eBay for a handcrafted Harry Potter wand. He sent me a stick. He went into his backyard, he picked up a stick.
Howard: It's numbered.
Raj: Ooh, limited edition. Nice.

(After Sheldon passes out after the Halloween prank)
Howard: who had there money on faint?
Raj: I had pee his pants.
Leonard: Hang on, looks like everyone's a winner.

Leonard: See that? I just saved us forty bucks.
Sheldon: I've long said what you lack in academic knowledge, you make up for in street smarts.

Howard: Someone has to go up with the telescope as a payload specialist and guess who that someone is.
Sheldon: Mohammed Lee.
Howard: Who's Mohammed Lee?
Sheldon: Mohammed is the most common first name in the world. Lee, the most common surname. As I didn't know the answer, I thought it gave me the mathematical edge.

Sheldon: Amy, the relationship agreement was not designed for either one of us to get our way.
Amy: You use it to get your way.
Sheldon: I use it to get the right way. The fact that the right way is also my way is a happy coincidence.

Sheldon: Hello Leonard, do you like my bongos?

Sheldon: Here.
Howard: What is this?
Sheldon: You're upset. The convention is to bring an upset person a hot beverage.
Howard: No, but what is it?
Sheldon: Chicken broth. It seemed culturally appropriate. Also, there was a single cube of chicken bouillon in the cupboard when I moved in and it's been bothering me for the last eight years. So, as they say, two birds.

Leonard: Obviously, when I saw that you were in ours, I went and used another one.
Sheldon: Where?
Leonard: The gas station across the street.
Sheldon: In your pajamas?
Leonard: Yes.
Sheldon: Without shoes?
Leonard: Yes.
Sheldon: On a cold winter's night?
Leonard: Yes.
Sheldon: Seems unlikely. Did you bring your asthma inhaler?
Leonard: Uh, uh, uh. Yes, I did!
Sheldon: Well, then, I guess it's plausible.

Penny: And yes, you love correcting people and putting them down.
Sheldon: Au contraire. When I correct people I am raising them up. You should know, I do it for you more than anyone.
Penny: Come on, you do it to feel superior. I see that twinkle in your eye when someone says who instead of whom or thinks the moon is a planet.
Sheldon: Or Don Quixote is a book about a donkey named Hotay.
Penny: See, there it is, there's that twinkle.
Sheldon: Well, I can't help it. That's an involuntary twinkle.

Leonard: No, I was gonna grab Raj and Howard and have a good time.
Stuart: Oh, great, more guys. It's gonna be another Wil Wheaton sausage-fest.

Penny: Well, I already talked to Raj, but I wanted to apologize to the rest of you for, you know, everything.
Raj: Please, Penny, let me. We've decided to let our crazy, wonderful night together be just one of those memories you have and can call to mind when you're feeling blue or you're in the shower. (places a hand on Penny's shoulder)
Penny: Hey, what you doing, Quick Draw?
Raj: Sorry. Go on.

Penny: How was the wedding?
Amy: Great. Until I accidentally made Leonard fall in love with me.
Penny: Come in, let's talk. Do you want a glass of wine?
Amy: Wine is one of the reasons I'm in this fix. That and this dang pelvis.
Penny: Okay, I'm sorry, what exactly happened?
Amy: The inevitable. He was lonely and vulnerable from missing his girlfriend, while I was charming, supportive and, let's face it, in this dress, the perfect combination of Madonna and whore.