Leonard: See this right here. What you're doing. Can you please not do that around Sheldon's mom?
Beverly Hofstadter: Why, are you attracted to her, too?

Leonard: I change my answer. It's amazing. It's hot. We can barely keep our hands off each other.
Beverly Hofstadter: Seems odd to try and impress your mother with your sexual prowess. But then, you always did have that unresolved Oedipal complex.

Beverly Hofstadter: So, have you and Penny set a wedding date?
Leonard: No, we're kind of taking it slow.
Beverly Hofstadter: I see.
Leonard: What does that mean?
Beverly Hofstadter: You've been on and off with this woman for seven years and engaged for one year. One has to wonder if there's a problem. Are you having satisfactory intercourse?
Leonard: Yes, Mother.
Beverly Hofstadter: Only satisfactory. I see.

Sheldon: Leonard's mom is a renowned psychiatrist and woman of science. Can you please keep the Bible babble to yourself while she's here?
Mary Cooper: Are you ashamed of me?
Sheldon: Of course not. I love you. I'm just embarrassed by the things you believe, do and say.
Mary Cooper: Well, I love you, too, my little bowl of lion chow.

Mary Cooper: I tried to read your paper, but it was very hard for me to understand.
Sheldon: Oh, it's quite straightforward, actually. It describes a new model of the universe that conceptualizes it as the surface of an n-dimensional superfluid.
Mary Cooper: Interesting. You can believe that, but God filling an ark with animals two-by-two is nonsense.
Sheldon: What did they feed the lions, Mother?
Mary Cooper: The floating bodies of drowned sinners, of course.

Amy: Do you think the moms will get along?
Leonard: I don't know. They're pretty different.
Sheldon: Maybe they'll be best friends. One of them is brilliant, one is sweet and simple.
*to Leonard*
Sound familiar?

Penny: You know, your mom's never been too thrilled with our relationship. Maybe I should get her something so she warms up to me.
Leonard: If you could run out and get a PhD, that might make her like you.
Penny: Really? It didn't work for you.

Amy: Sure, his mom gets roses. When I want them, they're a "bouquet of severed plant genitals."
Sheldon: You act like I didn't get you that mushroom log on Valentine's Day.
Amy: He's right. Roses die, but a moist rotting log will pump out mushrooms for two or three magical years.

Amy: It's so nice both of your moms are coming in to see you guys get an award.
Sheldon: Well, my mother's been there for every honor I've won since I beat out my twin sister for the Did It on the Potty trophy.

Penny: Leonard, what time does your mom's plane get in?
Leonard: I don't know. Sometime tomorrow morning.
Penny: Don't you want to know for sure?
Leonard: No need to. As soon as she flies into California airspace, I'll feel a disturbance in the Force.

Leonard: So you really think they liked it?
Penny: Oh, sweetie, it was the best speech I--
*Drone comes through the door, knocking Penny and Leonard off their feet*
Sheldon: Don't worry, everyone in here is safe.

Tech Support: Tech Support. Can I help you?
Sheldon: Yes, it's a robot uprising! Call the police!

Howard: What happened to me? When did I become an old man baffled by modern technology? Next thing you know, I'll be hitching my pants up to my armpits and complaining about the awful music the kids are listening to.
Sheldon: It is awful, isn't it? Listen to that noise.

Leonard: So, for the remainder of my speech, this is for the invisible kids. Maybe you never fit in. Or maybe you were the smallest kid in the school. Or the heaviest. Or the weirdest. Maybe you're graduating and you still haven't even had your first kiss. By the way, nineteen, and Geraldine Coco, wherever you are, thank you. Maybe you don't have any friends, and guess what, that's okay. While all the popular kids are off doing whatever - I don't know what they're doing because I was never there.

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.