Raj: Aren't you going to get 3D glasses?
Sheldon: I brought my own. No sense in risking "bridge of nose Herpes".
Raj: Is that a real thing?
Sheldon: Well, until they invent nose condoms, I'm not finding out.

Sheldon: I believe the painful sensation felt after passing a meal of spicy chillies is proof that the rectum does possess the sense of taste.

Sheldon: As hard as this is I have to move on. I can't keep postulating multi-dimensional entities and get nothing in return. I have needs too!

Sheldon: Play. Play. Play. Play. Play.
Leonard: What are you doing?
Sheldon: Trying to use a Jedi mind trick to control Stephen Hawking. Play. Play. Ugh! He must be wearing a tinfoil hat or something.

Sheldon: I'm gonna need some help. Someone baby-proofed the front door.

Amy: I think you need to do some editing, like maybe cut out all that stuff about your childhood.
Sheldon: Are you kidding? Growing up in the backwoods of East Texas is what makes me warm and relatable.
Amy: Well, what about all these pages calling out everyone who said you wouldn't succeed?
Sheldon: I told them all they would rue the day. How is it gonna make me look if the day finally comes, and they're not filled with rue?

Leonard: You know what, go to Hell and set their thermostat.
Sheldon: I don't have to go to Hell. At 73 degrees, I'm already there.

Sheldon: Okay, stop ruining Valentine's day and order my pizza.

Sheldon: All right, Amy, you're up. Next decision.
Amy: Come on, first dance! Come on, first dance!
Sheldon: (runs computer randomizer) Invitations! Oh! That's a good one. Just a suggestion, hologram projected out of R2-D2.

Sheldon: (Yelling at a mockingbird) And you, the notes are C, D, E, G and A! You pick one or I'm chopping down that tree!

Sheldon: Wait, is this really worth it? We've lived together for years without ne'ery an argument, but we start talking about a table and suddenly we're at each other's throats.
Leonard: Ne'ery an argument?! Ne'ery!?!
Sheldon: That means not one or not any. Maybe instead of a table you should buy a dictionary.
Sheldon: (To himself) Well, I don't know whether I won that but at least he's upset.

Shopper: Which hard drive do I want? Firewire or USB?
Sheldon: It depends on what Bus you have.
Shopper: I drive a Chevy Cavalier.
Sheldon: Oh my God.

Shopper: Excuse me, do you know anything about this stuff?
Sheldon: I know everything about this stuff.

Sheldon: I see. You're putting your future bride's happiness above mine.
Leonard: Well, yeah!
Sheldon: Wow.

Raj: And we're blending, and we're blending, and we're done. Sheldon: I know Mr. Data isn't supposed to smile, but here it comes. Howard: (Dressed as a Borg) Come on, guys. Let's do this. Leonard: (dressed as Captain Picard): Yeah, I'm sweating my bald cap off.