Sheldon: 'He drank from Leonard`s glass' - the words they will be carving into my tombstone.

Penny: Are you saying that Amy is, oh, what's the scientific word-
Sheldon: Forget science: she's horny.

Penny: Sheldon, you can't re-program people.
Sheldon: No, you can't re-program people.

Leonard: What makes you think she wouldn't have sex with me? I'm a male and she's a female.
Sheldon: Yes, but not of the same species.

Leonard: Okay, I know what you're doing.
Sheldon: Really?
Leonard: Yes, you're using chocolates as positive reinforcement for what you consider correct behavior.
Sheldon: Very good. Chocolate?
Leonard: No, I don't want any chocolate! Sheldon, you can't train my girlfriend like a lab rat.
Sheldon: Actually, it turns out I can.

Leonard: I can't believe I'm spending my wedding night with you.
Sheldon: Really? I never imagined it any other way.

Sheldon: I have a masters and two PhDs. I should not have to do this.

Sheldon: Leonard, as soon as we get home, I want to have coitus with Amy. [checks for Amy's reaction] Okay, she can't hear.

DMV Worker: Here's your learner's permit. Go away.
Sheldon: But I'm not done. I have many additional concerns about these questions.
DMV Worker: Don't make me climb over this counter!

Sheldon: But I have been getting better with sarcasm, if you want to give that a try.
Amy: *sarcastic* Oh, sure, I'd love to.
Sheldon: Whenever you're ready.

Sheldon: Well, this is very pleasant.
Leonard: I'm glad you're enjoying yourself.
Sheldon: And you said there would never be enough pasta for the three of us.

Bernadette: Come on, it could be romantic. The two of them away together, keeping each other warm in snowy Wisconsin.
Sheldon: Oh, no, no, no, no. She'd be going alone. If you think I'm scared of birds, you should see me around sheep.

Sheldon: Do you want to say it?
Amy: Let's say it together.
Sheldon and Amy: We're getting a turtle!

Sheldon: Well, this is different. Candles and music.
Amy: Do you like it?
Sheldon: It's kind of spooky.
Amy: I can change it back.
Sheldon: No, it's your birthday. As long as no one jumps out in a hockey mask, I'll be fine.

Sheldon: What's that animal doing in our apartment?
Leonard: She's in her crate, she can't get out.
Sheldon: I have two words for you: Jurassic Park.