Leonard: Just tell me the truth, Mother. Was my whole childhood just one big experiment?
Beverly Hofstadter: Of course not, dear. It was thousands of small experiments.
Leonard: So that's all I was to you, a-a test subject?
Beverly Hofstadter: No, you were my baby and I found you fascinating.
Leonard: Really?
Beverly Hofstadter: Yes, watching you develop, tracking your progress. I know I'm not the warmest of parents, but it was time we spent together, and, honestly, those are some of my fondest memories.
Leonard: When did you stop?
Beverly Hofstadter: Oh, I can't tell you. The experiment isn't over.

Bernadette: Look, I think that's LeBron over there.
Penny: James?
Bernadette: No, LeBron Kershenbaum.

Penny: So when was the last time you saw Howard in his astronaut uniform?
Bernadette: About a week ago.
Penny: Really? What was the occasion?
Bernadette: Date night. We do a little role-playing.
Penny: What role do you play?
Bernadette: (Russian accent) I am Ykatarina Nazdorovya, lonely Russian cosmonaut who is expert at physics and making love.
Penny: Okay, that just made the next hour really weird.

Leonard: Okay, what would you do?
President Siebert: I'd find some sap and put him in charge so I wouldn't have to be the bad guy.
Leonard: That's a really good id-- Oh.

Raj: Wait, wait, so you don't know what their fight was about?
Georgie: I wish I could help you, boys. But, you know, Sheldon used to keep an enemies list when he was a kid.
Leonard: Oh, he still does.
Georgie: Really? I figured that went the same way as his bathroom schedule.
Howard: If you mean digitized, annotated and put online, it did.
Georgie: Maybe that'll tell you something. Hey, while you're looking at it, if I'm still on there for peeing in his shampoo bottle - Eh, you know what, just leave it.

Sheldon: Now, do you know what Leonard and Penny got us for our wedding gift?
Howard: Well-
Sheldon: Don't answer. I don't want to know. I just want to know if you know.
Howard: I do know.
Sheldon: Okay, great. I believe that Amy and I have figured it out. Is it a clue to a scavenger hunt that will lead us to the actual present?
Howard: If you're asking if you and Amy should spend the next couple days running all over town searching for the next clue, I'm gonna have to say yes.
Sheldon: I knew it! This is so much fun.
Howard: Oh, it really is.

Sheldon: It's so funny, we did all these experiments on them and they didn't even notice.
Amy: I know, I was worried it would be obvious, but it wasn't.

Raj: Recently, 12 new moons were discovered orbiting Jupiter, bringing the total up to 79.
As a middle child myself, I'd like to extend my sympathies to moons two through 78. Your grandpa will never learn your name. I'd like to thank you for joining me on this journey through the stars. If you enjoyed this lecture, please come back Thursday for the exact same one.

Ms. Davis: Thank you both for coming. President Siebert asked that I be a part of this conversation to help us calmly discuss what went wrong and how we can better move forward. We are not here to point fingers, so, Dr. Cooper, please stop that.

Bernadette: Why don't you want to work with me? I know I can be tough, but that's just 'cause I'm surrounded by useless idiots.

Leonard: Sheldon, that was really rude.
Sheldon: I'm sorry. Amy is the one constant I can count on, and now she's changing.
Leonard: It's just a haircut and some clothes.
Sheldon: No, it's the last straw! I can't take any more! [elevator bell dings]
Penny: Can you believe it? They finally fixed the elevator.

Howard: Hey, have you checked the dates on these? They're all expired.
Stuart: You buy candy in a comic book store, you get what you get.

Amy: You're really letting your father pick out a wife?
Raj: Why not? Arranged marriages have been working for thousands of years. Anu and I come from similar backgrounds, our families get along and we each filled out questionnaires, so we know we're not wasting our time with someone who's not compatible.
Penny: Oh, that sounds so dry and clinical.
Sheldon: You lucky duck.

Howard: Wow. I wonder what that guy could've done to make Sheldon not talk to him for 20 years.
Leonard: I wonder if it'd work a second time.

Howard: William Shatner, Kevin Smith. Who else could be there?
Leonard: Do you see what I see over his shoulder?
Howard: Is that a ghost?
Raj: I think it's Stuart.
Sheldon: That is Stuart. What-What's he doing there?
Raj: Maybe he died in Wil's house and he can't leave until he solves his own murder.