Sheldon: Thankfully all the things my girlfriend used to do can be taken care of with my right hand.

Leonard: I'm not being weird. Am I being weird?
Sheldon: Yes. And that's coming from me.

Penny: Oh, it's Leonard. He says Sheldon's drunk and they're gonna do karaoke if we want to join them.
Penny: That sounds fun.
Amy: Oh, no. Sheldon's drunk texting me.
Bernadette: What's it say?
Amy: "Would you like to sing karaoke with us."
Bernadette: How is that a drunk text?
Amy: He used a period instead of a question mark. He's so wasted.

Sheldon: Perhaps I should explain. While working with Koothrappali, we discovered an asteroid, and I named it after you.
Amy: Oh, Sheldon, thank you. That's so romantic. But what about Rajesh? He was okay with you choosing the name?
Sheldon: Well, it took a little negotiating, but I wore him down. Uh, we get the asteroid, and if you and I have children, they all have to be named Rajesh.
Amy: All of them?
Sheldon: Even the girls.
Amy: Okay, I think I know what to say now.

Penny: Come on, Amy, show us the dress.
Amy: Okay, but I'm really stepping outside of my comfort zone here.
Penny: Uh, I don't think any of your comfort zones are showing.

Howard: I love you. And I'm not just saying that because your breasts are gonna get bigger.

Sheldon: Hello.
Leonard: Hey, buddy, can we have some privacy?
Sheldon: Of course. Wouldn't want to intrude. (takes red bra out of his pocket and hands it to Penny) This is yours.
Penny: Okay, when I'm done with him, I'm gonna need more information.
Sheldon: Nothing odd. I just wanted to rub Amy's nose in it.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Leonard: Penny. We are made of particles that have existed since the moment the universe began. I like to think those atoms traveled fourteen billion years through time and space to create us, so that we could be together and make each other whole.

Howard: If you don't want to use dating Web sites, what do you suggest?
Sheldon: Off the top of my head? Prospective women weed themselves out in a battle of wits until only one champion remains, she shows up at my door flush with the thrill of victory, and then sits quietly by my side while I watch Daredevil.
Howard: You seriously think women would fight for you?
Sheldon: People compete for jobs and trophies, why not me?
Howard: He's right. He knows a lot of jokes.

Penny: Well, what's the third option?
Sheldon: That I have coitus with her.
(Penny's wine glass smashes in her hand)

Howard: You know what's really happening here? Your girlfriend is breaking up our band.
Raj: She has nothing to do with this. I am my own man.
Howard: Oh, please. Your brain belongs to whoever's willing to sleep with you.
Raj: That is so not true.
Howard: Really? Remember when you were gonna get circumcised for Rachel Bernstein?
Raj: That had nothing to do with Rachel. It was an overreaction to a bad zipper injury.

Amy: I've seen and talked to you more in the two days we've been broken up than in the last two months we were together.
Sheldon: Well, if you want to see less of me, maybe we should go out again.

Amy: Uh, well, actually, to be honest I haven't told her yet.
Penny: You've been giving me a hard time and you haven't even told your mom about Sheldon?
Amy: I'm feeling a little dizzy from all the blood loss. I don't know what you're talking about.

Raj: My name is Little Orphan Annie. You killed my father. Prepare to die.
Howard: My name is Darth Vader. I am your father. Prepare to die.