Sheldon: All right, this goes against everything I stand for, but desperate times call for desperate measures. (Kneels down to pray) Lord, this is Sheldon Cooper, you're good friends with my mom. I know I've spent my life denying that you exist-
Howard: Got them!
Sheldon: -and I will continue do so!

Alfred Hofstadter: Well, on that note, there are many cultures that have an apocalyptic flood as part of their mythology.
Mary Cooper: I don't have a mythology. I have the unerring Word of God. But that's very interesting.
Alfred Hofstadter: Oh. I, I didn't mean to disparage your faith. Actually, I admire it.
Mary Cooper: Really?
Alfred Hofstadter: Yes. Yes, I'm an agnostic myself. But I have prayed many times to God, to turn my wife into a pillar of salt.
Mary Cooper: Well, He came close. Turned her into a giant block of ice.

Raj: My name is Little Orphan Annie. You killed my father. Prepare to die.
Howard: My name is Darth Vader. I am your father. Prepare to die.

Amy: Uh, well, actually, to be honest I haven't told her yet.
Penny: You've been giving me a hard time and you haven't even told your mom about Sheldon?
Amy: I'm feeling a little dizzy from all the blood loss. I don't know what you're talking about.

Howard: What kind of music are you thinking of?
Stuart: I like all kinds of music, but my favorite genre is free.

Leslie Winkle: Uh, in the past, I would've said something obnoxious, like, "Happy birthday, dumbass". But I'm not gonna do it. You and I have both grown a lot, and it's just so nice to see you all again. So happy birthday, Sheldon.
Sheldon: Oh. Oh, now, you know I hate change. Say it.
Leslie Winkle: Happy birthday, dumbass!

Raj: Have you guys seen this feature that lets you talk to Siri without pressing any buttons?
Howard: No. How does it work?
Raj: You just say, uh, "Hey, Siri, what time is it?"
Siri: The time is 6:37 p.m.
Howard: So now anyone can control your phone? Hey, Siri, show me pictures of naked grandma butts.
Raj: Nice try. It only recognizes my voice.
Howard: Oh, cool. (Imitates Raj): Hey, Siri, show me pictures of naked grandma butts.
Raj: I don't sound like that.
Siri: Here are some images of naked grandma butts.

Sheldon: Well, this is different. Candles and music.
Amy: Do you like it?
Sheldon: It's kind of spooky.
Amy: I can change it back.
Sheldon: No, it's your birthday. As long as no one jumps out in a hockey mask, I'll be fine.

Amy: Let's see. I have been on six dates with three different people. It was either for coffee or dinner. One I met at a bookstore and two I met online. I haven't slept with anyone. The aquarium is 40 minutes away. And there's a baggie of Cheerios for you in the glove compartment.
Sheldon: Uh, regular or honey nut?
Amy: I mixed them.
Sheldon: You mixed them. No wonder gentleman callers are pounding down your door.

Sheldon: Well, I enjoyed that more than I thought I would.
Amy: Me too!
Sheldon: I look forward to your next birthday when we do it again!
Amy: That works for me.

Penny: You guys just got back together. You might not want to ditch her on her birthday.
Leonard: I think Penny has a point. You can see it another day.
Sheldon: But someone might spoil the movie. No one can spoil Amy's birthday for me. Surprise, she's even older. Who saw that coming?
Penny: Aww, that's nice. Put that on her cake.

Sheldon: This is Leonard. He's your best friend in the world.
Leonard: All right, just stop. This is ridiculous.
Sheldon: Sometimes he gets cranky, but you can trust him with your life. And he does more things for you than I can even begin to list.
Leonard: Thank you.

Leonard: I love you.
Penny: Who cares?

Raj: But, Amy, when you and Sheldon split up, didn't you start dating someone right away? Amy: Well, I ... I wouldn't say right away.
Sheldon: And actually, it was three different men.
Barry Kripke: Three different men?! Damn, girl, way to give the milk away!

Sheldon: Your friends? I think you mean my friends. And why wasn't I invited to this?
Amy: Maybe because the two of us being there would make them feel awkward.
Sheldon: We make everyone feel awkward. That's our thing!