Leonard: I know what you're doing. You don't want me going on this research trip because you're afraid to be alone.
Sheldon: I'm not afraid to be alone. On land. On the sea, it would be terrifying. Because of all the drowning.

Leonard: Look, I appreciate your signature blend of concern for me and incredible selfishness. If I get the chance to do this, there is nothing you can say that's going to stop me.

Raj: If you look carefully at Venus, you should be able to see the International Space Station pass by.
Lucy: Wow. Your friend was actually up there?
Raj: Yeah. He brought me back a T-shirt that said "My Friend Went to the Space Station and All I Got Was This Lousy T-Shirt".
Lucy: Did he take the T-shirt to space?
Raj: Nope. It's exactly as lousy as advertised.

Leonard: So, listen, do you remember when I said the similarities of the equations of general relativity and hydrodynamics suggest you could find the equivalent of Unruh radiation in a large body of water?
Penny: I thought I said that to you.

Leonard: I'll be on a ship in the North Sea.
Penny: On a ship? Aren't they afraid Hawking will just roll overboard?
Leonard: Uh, he's not gonna be there. He's just sending a team to research his theory.
Penny: Oh, sure. Like when you send me to kill spiders in your bathtub.

Penny: Oh, sweetie, if you're gonna screw things up, it's gonna be while you're here, not while you're away. No. I mean, look, you have to go. It sounds like an amazing opportunity. And I'm just basing that on how much I didn't understand what you said about it.

Leonard: Really, you guys do not need to throw me a going-away party.
Howard: Are you kidding me? How often can you say bon voyage to somebody when they're actually going on a voyage?

Leonard: Anyway, you guys really don't need to make a big deal.
Sheldon: Leonard, you're being selfish. We need to give you a proper send-off so we'll have closure when you die at sea and crabs eat your face.
Penny: Sheldon, sweetie, shut up.

Amy: Ignore him. He's a little nervous 'cause he doesn't think I understand the severity of your social anxiety.
Raj: What the? Are you crazy? You can't talk about social anxiety to someone who has social anxiety. It makes them socially anxious!

Bernadette: So, have you ever spent a long time on a boat before?
Leonard: Yeah.
Penny: Are you referring to the time we got stuck on the Small World ride at Disneyland?
Leonard: Yeah.

Howard: I'm proud of you, Leonard. Working out on the North Sea for months, that's really something.
Leonard: I know. As far as science goes, this is the adventure of a lifetime.
Howard: Maybe your lifetime. I went to space.
Leonard: It's not a competition.
Howard: You're right, you're right. I'm really proud of you, and I'm gonna miss you when you're gone. And space beats water.

Howard: It was really nice of you to try to be happy for Leonard.
Sheldon: Thank you.
Howard: It must've killed you when I went to space.

Sheldon: Penny, we’re in the red zone. The white zone is for loading and unloading. We’re breaking the law.

Barry Kripke: I'd love to babysit for you. Kids love me. Something about me just makes them waff and waff.

Sheldon: I'm not interested in being published in Mad Magazine. Zingers fly fast in the Thunderdome, Barry.