Penny: Fine. You think you know so much. Who's my favorite Spice Girl?
Leonard: Baby.
Penny: Who's my favorite member of NSYNC?
Leonard: Justin.
Penny: Who's my favorite Backstreet Boy?
Leonard: (Scoffs) Nice try. NSYNC forever.
Penny: Damn it!

Elon Musk: Nice to meet you, Howard. Feels great to come down here and help the less fortunate, huh?
Howard: Oh, yeah. Nothing better than helping people.
Which is something I realized when I was viewing Earth from the deck of the International Space Station, where I spent two months as a payload specialist, a job I was qualified for because I'm an MIT-trained engineer.
Elon Musk: And I thought I ladled the gravy on thick.

Penny: Do you even like the Beach Boys?
Sheldon: They have "beach" right in the name. What do you think?

Raj: And you know we get to name it.
Sheldon: We better choose a name no one can make fun of. Sir Frederick William Herschel didn't do Uranus any favors.

Howard: What is happening? Are we missing him?
Bernadette: No, that's not what this feeling is. Is it?
Howard: Of course not. He drove us crazy. Like when you were gonna make that pie and Stuart ate all the blueberries.
Bernadette: And he tried to deny it, but his teeth were all purple.
Howard: That was pretty cute.
Bernadette: Yeah. Eww, we are missing him!

Bernadette: I brought you a little care package from work. It's our latest antiviral and the best decongestant we make.
Sheldon: I hope laughter is the best medicine, 'cause this care package is a joke.
Howard: Hey, she came all the way here- (Sheldon sneezes on Howard)
Bernadette: (Handing Howard the care package) You're gonna want to take these with food.

Meemaw: Sheldon, tell this girl that my ring will never be on her finger.
Sheldon: Yeah, I'm gonna opt out of that one, too.

Sheldon: I always looked up to you and Pop-Pop. I know what a challenging man he could be, but I saw you stand by him and make him into a better person.
Meemaw: I did.
Sheldon: Yeah, well, that is exactly what I've been doing the last five years with this little work in progress.
Leonard: He never disappoints, does he?

Sheldon: What is it?
Amy: Well, your birthday's coming up and you've never let us celebrate it. And I was hoping maybe this year we could.
Sheldon: Oh, I suppose that's a discussion we could have. (Sheldon runs back up the stairs)
Amy: Okay, great, I mean, it doesn't have to be a big party or anything. I was just - Where'd he go?

Sheldon: Very well. You may celebrate my life by throwing a party with cake, presents and a shower of admiration and love. But then you owe me big-time.

Penny: Uh-oh, somebody's still pouting.
Leonard: Leave me alone.
Penny: If it's because you lost a stick, I know where it went.

Penny: Yeah, come on, Raj.
Raj: Wait, did Amy make her spinach dip?
Sheldon: She did.
Howard: And I'm gonna eat it all!

Zack: Boy, you get some dirty looks over there when you ask for ice.

Zack: Oh, man, I didn't mean to do that. But I do appreciate you recognizing my swimmer's body. Which, incidentally, I got from playing Marco Polo at the YMCA.

Sheldon: Oh, and lastly, please initial here to confirm that ownership of the living room couch is hereby transferred to me in perpetuity all throughout the universe and all alternate universes except for those universes where owning a couch is forbidden by the hive queen. In which case, all glory to the hive queen.