Bernadette: But I thought I'd be more excited.
Dr. Koothrappali: Oh, being excited isn't a guarantee of anything. Rajesh's mother was thrilled when she was pregnant with him. After he was born, she doted on his every move. And you know what happened? He broke her heart, moved halfway around the world, and dates only poor white women. So you never know.

Sheldon: So Bernadette, if I express interest in your baby will you promise not to make me touch it?
Bernadette: Sure.
Sheldon: Hey, how's life with your baby?
Amy: Really? You're never gonna touch their baby?
Sheldon: To this day I've never touched Stuart.

Leonard: It's not just Howard and Bernadette. I mean, look how far we've all come.
Penny: Hmm.
Stuart: You two got married.
Amy: Sheldon and I are living together.
Sheldon: But if my mom asks, we have bunk beds.
Leonard: Penny was a struggling actress when we met, and now she's a successful pharmaceutical rep.
Penny: Okay, you don't have to say "struggling" every time. You can just say actress.
Stuart: Howard went to space.
Amy: Bernadette got her doctorate.
Leonard: Sheldon, Howard and I are working with the government on our quantum gyroscope.
Amy: We've all come a long way. There's a lot to be proud of.

Amy: What are you looking at?
Sheldon: Comments from our Behind the Flags retrospective. Get this, people are calling it "the longest one yet".

Sheldon: No matter where I am, this will always be my spot.

Penny: You can stay in Leonard's room, and we'll stay at my place.
Amy: You're sure that's not an inconvenience?
Penny: No, not at all.
Leonard: And we live with Sheldon, so the word "inconvenience" has really lost all meaning.

Bert: Hey. Looks like I got stood up, so I'm gonna head out.
Amy: Oh, no. Are you sure you don't want to give her a few more minutes?
Bert: Nah, G-Harmony recommends after two hours, it's time to cut bait.

Sheldon: I may have lost my guidance system and my girlfriend, but I still have a colon full of yesterday's meals to keep me company. Although, thanks to your high-fiber breakfast, I'm sure that'll be leaving me, too.

Amy: Comfy?
Sheldon: Oh, I'm just happy I don't know what this memory foam remembers.

Penny: She said not to come. It's gonna be a while.
Amy: (sighs) Well, first deliveries can be slow.
Sheldon: I am starting to rethink the Flash onesie I bought this kid.

Sheldon: Uh, I know it's not your birthday, but if you're interested-
Amy: I am.
Sheldon: Okay. Oh, and just to be clear, I'm not being intimate with you in order to keep you from going.
Amy: I wasn't thinking that.
Sheldon: Well, no, it's just, I'm just warning you, you know, if you find yourself 3,000 miles away and craving a hit of this, you know I can't Skype it to you.
Amy: That's a risk I'm willing to take.
Sheldon: All right, then.

Bernadette: You know, I just read that a team at MIT developed a device that helps people read human emotions.
Leonard: And you think we can get those guys to reprogram Sheldon? Cool.

Amy: Aww, I remember signing our first Relationship Agreement.
Sheldon: You seem to be forgetting the "no nostalgia" clause.

Raj: I'm the son of a gynecologist. I could be helpful.
Bernadette: It would help if you stopped telling me I have a textbook cervix.
Raj: The polite response is, "Thank you for noticing."

Lucy: Can I just say something? Going out with Raj was one of the best things that ever happened to me.
Raj: Yes, I'll take you back.
Lucy: It's like I needed to go through that experience to know what exactly I don't want in a man.
Raj: That's hard to hear, but I'll still take you back.