Bernadette: Every time we eat dinner here, your mother refuses to let me help with the dishes.
Howard: Don't take it personally. She likes doing them by herself so she can lick the plates with no one looking.

Bernadette: You ready to go?
Howard: Yeah, let me just grab a couple of fresh turtlenecks.
Bernadette: I don't understand why you keep your stuff here when there's plenty of room at home.
Howard: What are you talking about? All I have here is a few sweaters, books, bank stuff, computers, mail, collectibles, medicine and my electric body groomer. Ooh, there's my plaid dickie. Oh, got this at the Goodwill store for 50 cents. Can you believe it?
Bernadette: 50 cents sounds right.

Leonard: Hey, look who's out after dark, like a big boy.
Sheldon: I was out raising heck with Mr. Wil Wheaton. Four hours more and we would have closed down the HomeTown Buffet.
Leonard: I thought you had plans with Amy.
Sheldon: Yeah, I did, but then Wil called Amy a pain in the A-S-S. She got huffy and left, then Wil and I headed out to dinner. That place really did remind me of my hometown. Because there we also have a HomeTown Buffet.

Sheldon: I've been thinking about what happened, and I hope this gift will make things better.
Amy: Star Trek DVDs? Why would I want this?
Sheldon: First of all, you're welcome. And furthermore, not being familiar with Wil Wheaton's body of work, there was no way for you to know you were being rude to a national treasure. Get ready for 130 hours of I told you so. (Amy returns the DVDs and slams the door) Fine. I'll just tell you what happens. Episode one, Encounter at Farpoint. Fade in. The new Enterprise heads out on its maiden voyage to contact the Bandi people of Deneb IV. Enter Wesley Crusher, played by my buddy ... (Amy opens the door, grabs the DVDs, and slams the door again) She's hooked.

Sheldon: Hello, I'm Dr. Sheldon Cooper. Welcome to Sheldon Cooper Presents Fun with Flags. Get ready for a very special episode where we explore the flags of the popular entertainment franchise, Star Trek. And to help us, I’m pleased to introduce a special guest, surprisingly, it only took gas money and the promise of free food to get him here, Mr. LeVar Burton.
LeVar Burton: Hey, Sheldon, it's a pleasure to be here. Well, we've got some interesting flags for-
Amy: Cut. Yikes, this guy is worse than Wil Wheaton.

Raj: Ooh, this is exciting. Like one of my classic murder mystery dinner parties.
Leonard: Right, the case of who murdered three Saturday nights of my life?
Howard: Colonel Koothrappali in the kitchen with the olive spread.
Raj: It was tapenade and you guys suck.

Penny: Look, he just moved here from London, okay? He doesn't really know anybody.
Leonard: Oh, good, an English accent, the sexiest accent you can have.
Penny: No, that's not true. There's French, there's Italian. No, you're right, it's the best.

Howard: What could he be doing in there every day for twenty minutes?
Raj: Well, he's not doing twenty-minute abs, because if he were, he would have better abs.

Raj: He is kind of a weirdo. Maybe he's got Leonard Nimoy chained up in there. Or Bill Gates. Or Stephen Hawking.
Howard: Why would he chain up Stephen Hawking?
Raj: Howard, please, you can't treat the man differently just because he's disabled. That's not okay.

Leonard: This is silly. I have nothing to worry about.
Sheldon: Oh, I don't know. I mean, statistically speaking, I'm sure you have something to worry about.
Leonard: What do you mean?
Sheldon: Well, if we assume your looks are average, right off the bat fifty percent of men on Earth are more attractive than you. That's 1.5 billion handsome lads standing by, waiting to rain on your parade.
Leonard: Well, yeah, but this isn't just about looks. I'm way above average in a lot of other things.
Sheldon: Not height, vision, athleticism or ability to digest dairy products.

Howard: When I was starting to do magic in junior high, I thought I could be an escape artist like Harry Houdini.
Raj: How did that work out?
Howard: Pretty good. I managed to escape friends, popularity, and every party thrown in a twelve mile radius.

Howard: What kind of secret does Sheldon have to encrypt?
Raj: He's always been very cagey about what he puts in his egg salad to make it so tasty.
Howard: It's paprika.
Raj: Really? Well, okay, one mystery solved.

Leonard: You, uh, moving in to the apartment on the fifth floor?
Cole: No, I was just visiting a friend.
Leonard: Oh, cool. The cute blond on four?
Cole: Yeah, you know her?
Leonard: I see her around. I like to keep my distance because her boyfriend is a pretty scary dude.
Cole: Really?
Leonard: Yeah. He's ganged up.
Cole: She told me he's a scientist.
Leonard: That's the name of his gang. The Scientists. They're crazy.
Cole: Well, thanks for the tip.
Leonard: No problem, brother. Stay frosty.

Alex: Oh, hello, Dr. Hofstadter.
Leonard: Hey, Alex, call me Leonard. Dr. Hofstadter is my father. And my mother. And my sister. And our cat. Although I'm pretty sure Dr. Boots Hofstadter's degree was honorary.

Howard: Forty-three. What is forty-three? Besides my mom's neck size.
Raj: It's the atomic number for technetium.
Howard: That stuff's radioactive.
Raj: Do you think he's building a bomb?
Howard: It took him two years to put together that Lego Death Star. I'm not worried.