Sheldon: Geology isn't a real science!

Sheldon: I was expecting applause but I suppose stunned silence is equally appropriate.

Sheldon: My friend Leonard said if I bothered you while you were eating, you'd think I was a creepy stalker.
James Earl Jones: Well, your friend Leonard sounds like a real weeny.
Sheldon: He is, Mr. Earl Jones. He is!

Sheldon: Leonard, I platonically love you, man, but face it, you're a mess.

Sheldon: Captain Hook's hand was eaten by a crocodile, not an alligator. If you're going to insult me at least get your facts straight.

Leonard: You're going march yourself over there right now and apologize.
Sheldon: Pfffft.
Leonard: What's funny?
Sheldon: That wasn't sarcasm?
Leonard: No!
Sheldon: Oh. Boy, you are all over the place this morning.

Sheldon: Do you even think about other people, Leonard?

Sheldon: She was a girl who was my friend who is now a girl who is not my friend.
Penny: Wow. That's like the worst country song ever.

Sheldon: I drank milk that tasted funny.

Penny: Helium.
Sheldon: Yes.
Penny: Yes.
Sheldon: Taylor Swift.
Penny: Yes. Pi.
Sheldon: Yes. Kardashian.
Penny: More specific.
Sheldon: Khloe?
Penny: Yes.
Sheldon: See, I remembered because if it looks like Kim it's Kim, if it looks kind of like Kim it's Kourtney, and if it looks nothing like Kim it's Khloe.

Sheldon: I'm sorry, are we really doing this? Or are we tricking him again like with the dinner party?

Sheldon: I'm glad to see you made it safely. How's your hotel?
Amy: It's not the best Best Western I've been to, but I'd say it's the third best Best Western I've been to.
Sheldon: I know how you feel. The Best Buy by my house is only the third best Best Buy.
They have the best buys, but having the best buys isn't the only thing that makes a Best Buy the best Best Buy.
Amy: What makes a best Best Buy the best Best Buy?
Sheldon: Mm, that's a great question. I like when they're next to a Chipotle.

Wil Wheaton: Sheldon, I was actually talking about when I was a kid on Star Trek.
Sheldon: How could you not like getting attention for playing Wesley Crusher? You were wonderful. A know-it all boy genius with an eidetic memory. Who couldn't relate to that?

Sheldon: Virgin diet cuba libre please.
Penny: OK.
Sheldon: In a tall glass with a lime wedge.
Penny: Oh I'll wedge it right in there.

Sheldon: And look over here, "shrimp in mobster sauce". What is mobster sauce?
Leonard: It's obviously a typo.
Sheldon: Perhaps. Perhaps this restaurant's now a front for organized crime. For all we know, the mobster sauce contains actual chunks of deceased mobsters.
Raj: No, no, no, no. I think it jut means it's the kind of sauce that mobsters like.
Howard: It doesn't mean any of that. It's a typo!