Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Zack: One question. How can you be sure it won't blow up?
Leonard: The laser?
Zack: The moon.

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Leonard: Don't worry about the moon. We, we set our laser to stun.
Zack: Smart.
Leonard: Now, we'll be able to see the beam when it leaves, but it won't be strong enough when it comes back to be seen by the naked eye.
Zack: (chuckling) Naked.

Sheldon: One ring to rule them all.
Rajesh: One ring to find them.
Wolowitz: One ring to bring them all.
Leonard: And in the darkness bind them.
Rajesh: Holy crap are we nerdy!

Leonard: I've always been a little confused about this. Why don't Hindus eat beef?
Raj: We believe cows are gods.
Sheldon: Not technically. In Hinduism, cattle are thought to be like God.
Raj: Do not tell me about my own culture, Sheldon! In the mood I'm in, I'll take you out, I swear to cow!

Wil Wheaton: Game over, Moonpie.

Sheldon: I made tea.
Leonard: I don't want tea.
Sheldon: I didn't make tea for you. This is my tea.
Leonard: Then why are you telling me?
Sheldon: It's a conversation starter.
Leonard: That's a lousy conversation starter.
Sheldon: Oh, is it? We're conversing. Checkmate.

Raj: If I could speak the language of rabbits, they would be amazed, and I would be their king.
Leonard: I hate my name. It has 'nerd' in it. 'Len. Nerd.'
Wolowitz: I lost my virginity to my cousin Jeanie.
Raj: I would be kind to my rabbit subjects. At first.

Raj: Okay, just to be clear, roller skating was my idea, and I'm very unhappy that you turned it into a double date. I hope you both fall on your asses and break your coccyxes.
Sheldon: The plural of coccyx is coccyges.
Raj: Screw you. Give me back my lima beans.

Wolowitz: You're such a douche
Raj: Who cares? You slept with your cousin!

Leonard: What would you guys do if you were me?
Wolowitz: I would take Sheldon to Switzerland.
Leonard: Seriously?
Wolowitz: Absolutely. And I'd leave him there.

Penny: So what do you say Sheldon, are we your X-men?
Sheldon: No, the X-men were named for the X in Charles Xavier. Since I am Sheldon Cooper, you will be my C-men.

Sheldon: Now remember, you were given powerful pain medication and a muscle relaxer, so don't operate heavy machinery, and try not to choke on your own drool. [goes to leave] Penny: Wait! You have to help me get into bed. [laughs] "Sheldon has to help me get into bed". Bet you thought I'd never say that!
Sheldon: Yes. Charmed. Your drug-addled candor knows no bounds. [helps Penny into bed]
Penny: You know people think you are this weird robot man who's so annoying all the time and you totally are. But then it's like that movie Wall-E at the end. You're so full of love and you can save a plant and get fat people out of their floaty chairs.
Sheldon: That's a fairly labored metaphor but I appreciate the sentiment behind it.