Raj: If this was Star Trek, we could use a phaser to blast it off.
Howard: No, it's too broad of a beam. You'd need something more precise, like Superman's heat vision.
Sheldon: Ooh, the Green Lantern's ring could make a big green hand that unscrews it.
Raj: If you need a green hand, why not just use the Hulk?
Sheldon: Oh, please, the Hulk would never get across the border with that temper.
Leonard: Guys, excuse me, not that calling one of the Avengers isn't a perfectly reasonable choice, but we're scientists. Don't you think we can figure this out using actual science?
Sheldon: Yes, we could use science. But it's your bachelor party. Lighten up.

Mary Cooper: I've always had a special place in my heart for Leonard. Taking care of my baby all these years.
Sheldon: Excuse me, I take care of him.
Mary Cooper: Sure you do.

Howard: I don't need this. I'm quitting the band!
Raj: Fine, I quit, too!
Howard: Then get out of my house!
Raj: With pleasure!
*door slams*
*Howard sighs*
Howard: Raj, wait!
Raj: What took you so long?

Penny: I think it's great you guys want to get more exercise, but do you really think sports is the right choice for you?
Leonard: What are you saying? We're not coordinated enough to play sports?
Penny: Okay, Leonard, sweetheart, you twisted your ankle playing Scrabble.
Leonard: I got a triple-word score with a double letter Q. If that's not a time to bust out the Scrabble dance, what's the point of having one?

Leonard: Well, how about we stop being so scared of losing each other, and just be together?
Penny: That sounds nice.
Leonard: Good. I've loved you from the moment we met and I will keep loving you until the end of time.
Penny: Oh my God, that is the most beautiful thing anyone's ever said to me.
Leonard: Yeah? That's because you're beautiful, and your beauty fills my heart with love and song.
Penny: Getting kind of cheesy, Leonard.
Leonard: You think that's cheesy? Buckle up.
(Leonard gets down on one knee)
Leonard: Penny Hofstadter, will you please stay married to me?
Penny: Oh dammit, you topped it.

Sheldon: No, not that. I understand the mechanics.
Professor Proton: Oh, good. Good. 'cause I have no idea what kids these days are calling their parts.
Sheldon: I think they say "junk."
Professor Proton: What is happening to this world?

Meemaw: Thank you, Moon Pie.
Amy: Uh, I'm curious. Why do you call Sheldon "Moon Pie?"
Meemaw: 'Cause he's so nummy-nummy.
Leonard and Penny: She could just eat him up.

Leonard: I'd love it if my dad could come.
Penny: Oh, you have to invite him. I haven't seen him since the divorce.
Leonard: Oh, he's like a different man. He stopped twitching, and I think he grew an inch and a half.

Sheldon: Raj, you were being a good friend, and my illness was no excuse for my behavior. I hope that you can accept my apology.
Raj: Of course I do.
Sheldon: And, Emily, I'm sorry for saying dermatologists aren't real doctors. And I'm sure you're tired of hearing that.
Emily: Do you honestly think I hear that a lot?
Sheldon: Well, I would imagine when your job is popping zits and squirting Botox into old lady faces-
Raj: Okay! Okay, the point is that we accept your apology.
Emily: Uh, maybe you do. He just insulted me again.
Raj: Yeah, but he doesn't mean it.
Emily: Why are you defending him?
Sheldon: I believe I can answer that. Uh, like me, Raj is demonstrating empathy.
Now, why don't you accept my apology, receive your free T-shirt, uh-- I hope extra small is okay. For some reason Wolowitz took a medium.

Penny: You could talk to her, and maybe if it comes up, you could ask if she's heard about the drug.
Leonard: What if I get caught?
Raj: Fear of failure!
Howard: Lack of confidence!
Sheldon: Kind of a wuss!

Leonard: Am I like the dryer sheets of your heart?
Penny: Better. You're the lint trap of my love.

Raj: Okay, and here's the hook. "Thor and Dr. Jones. Thor and Dr. Jones. One plays with lightning. The other plays with bones."

Dave: This is delicious.
Amy: Thank you.
Dave: Been a long time since I had a home-cooked meal.
Amy: When you were married, did your wife cook?
Dave: Not at first, no. But when she began cheating on me with a French chef, she became quite the wiz in the kitchen.
Amy: So, a little silver lining.
Dave: I suppose. Yeah, nothing takes the sting out of a shattered life like a properly-seasoned bowl of onion soup.

Leonard: I know what you're doing. You're trying to get attention so we'll feel bad for you, but it's not happening.
Sheldon: No, what I'm doing is trying to figure out how to live my life now that everyone is leaving me.
Leonard: Will you knock it off? We're across the hall.
Sheldon: As the kids are saying today, "talk to the hand."
Penny: They're not saying that.
Sheldon: They are in 2003.
Penny: No, no. They're really not.

Sheldon: I have a question about Batman. Batman is a man who dresses up like a bat. Man-bat is a part man, part bat hybrid. Now, if Man-Bat dressed up as a man to fight crime, would he be Man-Batman?
Leonard: No, he'd be Bat-Man-Bat.
Raj: But wouldn't Man-Batman just be a Batman that was bitten by a radioactive man?
Howard: But Batman is a man. You're talking about a man who would have the powers of a man. That's just Man-Man.
Sheldon: Well, isn't Man-Man just Man?
Leonard: But what if Man-Man dressed as a bat?
Raj: Well, that's just Batman.
Leonard: No, if a man dresses as a bat, that's Batman, but if Man-Man dresses as a bat, that's Batman-Man.
Howard: So does that answer your question?
Sheldon: Oh, I haven't asked it yet.