Amy: All right, you can open your eyes. I thought I'd let Harry Potter make things hotter.

Susan: Penny, I don't know what I was worried about. Your friends are just lovely.
Penny: Oh, thanks, Mom.
Susan: Although that Sheldon is a bit peculiar.
Penny: Is he? I never noticed.
Wyatt: He reminds me of that turkey we had who drowned looking up at the rain.

Sheldon: My pants are missing, I don't remember anything. Penny, this is your youth. What do I do?

Penny: This is getting old fast, Dolores, knock it off!
Sheldon: Uh, do you really think calling me names is helpful?
Penny: I do! Your life is fine, you big baby!
Sheldon: Maybe you're right.
Amy: Really?!
Leonard: If it helps, I'm questioning your life choices, too.

Amy: I've been smacking that ketchup bottle for a long time. All she has to do is tip it over and point it at her fries.

Amy: Listen, you and I are gonna be sharing a bed. You know, this is uncharted territory for both of us. How are you feeling about that?
Sheldon: Oh, excited, concerned, a little scared. All the same emotions I feel in line at Space Mountain.

Sheldon: Five minutes? We must be doing it wrong. It took us hours.

Sheldon: And just remember, I am proud of you and I support you in all that you do.
Amy: Thank you. That means a lot.
Sheldon: Oh, and one last thing. If you find yourself working with a male scientist who's as smart as me, as tall as me and has hair like Thor, well, then I want you to step away from the situation and call me immediately.

Penny: It's not that I want to go, I just think it'll make Leonard happy. And if I have to watch him squeeze into an Ewok costume, so be it.
Amy: Look at you, going to Comic-Con, talking about Ewoks. I really have become the cool one around here.

Stuart: Nice to see you again, Dr. Hofstadter. I'm, uh, Leonard's friend, Stuart.
Beverly Hofstadter: Nice to see you, too.
Stuart: Hi, I'm Stuart.
Alfred Hofstadter: Ooh, I'm Alfred, Leonard's father.
Stuart: Oh! Oh, hi. Uh, I'm sorry, did you two want to sit together?
Beverly Hofstadter: No!
Alfred Hofstadter: No!
Stuart: I was wondering why the front row was available.

Bernadette: Anybody have anything snarky to say about that? Didn't think so.

Penny: Uh, what's new?
Zack: Oh, tons of stuff. Put artificial grass in my backyard, got engaged, had a scary mole that turned out to be Sharpie.
Penny: Well, congratulations.
Zack: That's what my dermatologist said.
Penny: No, on getting engaged, good for you.
Zack: Oh, thanks.

Raj: Yeah, this military guy showed up at Howard's door. He was terrifying.
Sheldon: Oh no, what did he say?
Raj: He gave me his business card and asked me to please pass it along to Howard.
Sheldon: That doesn't sound terrifying.
Raj: Not to a white guy born here, no. To a brown guy whose name has a lot of syllables in it - terrifying.

Bernadette: You know, I just read that a team at MIT developed a device that helps people read human emotions.
Leonard: And you think we can get those guys to reprogram Sheldon? Cool.

Sheldon: I may have lost my guidance system and my girlfriend, but I still have a colon full of yesterday's meals to keep me company. Although, thanks to your high-fiber breakfast, I'm sure that'll be leaving me, too.