Missy: Hey, Shelly.
Sheldon: I'm so glad you made it, Missy. This is my fiancée, Amy. Amy, this is my sister. If I ever need a kidney, this is where you get it.

Ruchi: So, what do you guys do?
Raj: Well, I am an astrophysicist, so if you ever go out at night and look up at the stars, that's kind of my office. He sells comic books to children.

Stuart: Actually, I own my own store. Uh, if you'd like to check it out sometime, I'm running a new promotion: buy anything, get taken out for a reasonably priced dinner.
Raj: Yeah, yeah, Stuart's struggling financially. But he doesn't let that get him down. He believes in himself. Even though the whole world has made it clear he should not.

Raj: Do we know if there's life in the methane plumes of Enceladus or under the icy surface of Europa? Come back on Tuesday for my next show to find out. Spoiler alert: we don't.

Penny: I thought they fired you guys.
Sheldon: They did, but then they hired me back.
Leonard: Well, you better not be working on our project, because we're a team.
Sheldon: Leonard, there is no "I" in team. However, there is an "I" in "I'm working with the military and you're not." There's five of them, in fact.

Penny: Like, what'd you do last night?
Beverly Hofstadter: I had Cuban food at the home of a man with whom I shared unsatisfying intercourse.
Penny: Wow. Okay.
Beverly Hofstadter: And to anticipate your next questions, roasted pork and sideways missionary.
Penny: Sure. Sure. 'Cause you were full.

Penny: Oh, uh, hey, Beverly, you called my phone, not Leonard's.
Beverly Hofstadter: Actually, I was hoping to speak with you. Is this a good time?
Penny: Uh, that depends. What time is it where you are?
Beverly Hofstadter: Uh, just after 5:00.
Penny: (clears throat, and swaps fruit juice for a bottle of wine) Yeah, that counts.

Amy: Okay, how do you want to play this? Do you want to pretend like nothing's bothering you and blow up later, or do you just want to be a maniac right now?

Amy: What's with the blinking?
Sheldon: It's Morse code. So we can talk about without hurting --'s feelings.
Amy: Sheldon, I don't know Morse code.
Howard: I do. And if you have something to say, you can say it to my face.

Howard: Do you think Zack stole it?
Penny: No, he doesn't know how to steal Bitcoin. I mean, he waves at trucks.

Sheldon: I can't believe you don't care.
Professor Proton: Believe it.
Sheldon: Well, I care, a lot, and Wil Wheaton will rue the day he ever met me.
Professor Proton: I think that's true of most people.

Bernadette: But then we realized that it's a gift, in the sense that we didn't ask for it, and we may not have chosen it-
Howard: And we already have one.

Penny: Hey, I thought you were coming right back.
Leonard: I was, but we're both depressed, and decided to drown our sorrows.
Penny: With mouthwash? Man, that is so summer camp.
Sheldon: It's Romulan ale, from Star Trek.
Leonard: It was briefly legalized during the alliance between the Romulan Empire and the Federation at the time of the Dominion War.
Penny: Aw, now I'm depressed.

Bernadette: Can you get us a little snack?
Penny: You sure you don't want your spy to do it?
Howard: What are you talking about?
Penny: You really don't trust me? You had to have Amy stop by?
Bernadette: We trust you.
Howard: Yeah. You were a terrible waitress, and we still asked you to get us a snack.

Bernadette: Howie, slow down.
Howard: I can't. I'm not allowed to eat for 12 hours before my surgery, and I only got two more minutes.
Leonard: What surgery are you having?
Raj: I'm stress eating. My best friend's getting a vasectomy tomorrow.
Penny: And you're sad you won't be able to bear his child?